Abstract: The hybrid censoring scheme is a mixture of type-I and type-II censoring schemes. It is a popular censoring scheme in the literature of life data analysis. Mixed exponential distribution (MED) models is a class of favorable models in reliability statistics. Nevertheless, there is no much discussion to focus on parameters estimation for MED models with hybrid censored samples. We will address this problem in this paper. The EM (Expectation-Maximization) algorithm is employed to derive the closed form of the maximum likelihood estimators (MLEs). Finally, Monte Carlo simulations and a real-world data analysis are conducted to illustrate the proposed method.