含有持久生存数据的复发事件的生存函数的一个非参数方法

Nonparametric Estimation of a Recurrent Survival Function with Long-Term Survivors

  • 摘要: 在生物学、社会科学、保险理赔、可靠性和人口统计学等的研究中, 我们经常会遇到复发事件数据的处理. 最近一段时间以来, 两个相邻复发事件的时间间隔的一个纵向数据模型已经引起统计工作者的广泛兴趣. 本文中, 我们提议另一个复发事件时间间隔模型, 它可以用来模拟生存数据中带有所谓的持久生存者. 非参数方法将用于我们所提议模型的统计推断, 模拟和现实数据的例子将用来评价模型和提议估计方法的小样本性质.

     

    Abstract: Recurrent event data are often encountered in longitudinal follow-up studies related to biomedical science, econometrics, insurance claims, reliability and demography. The longitudinal pattern of gaps between successive recurrent events is often of great research interest. In this paper, we propose an alternative model which can accommodate ``cure fraction'' in gaps, and a nonparametric method is employed to the statistical inference. The proposed model and methodology are demonstrated by a small simulation result and the tumor recurrent data.

     

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