Abstract: Under inflation influence, this paper investigate a stochastic differential game with reinsurance and investment. Insurance company chose a strategy to minimizing the variance of the final wealth, and the financial markets as a game ``virtual hand'' chosen a probability measure represents the economic ``environment'' to maximize the variance of the final wealth. Through this double game between the insurance companies and the financial markets, get optimal portfolio strategies. When investing, we consider inflation, the method of dealing with inflation is: Firstly, the inflation is converted to the risky assets, and then constructs the wealth process. Through change the original based on the mean-variance criteria stochastic differential game into unrestricted cases, then application linear-quadratic control theory obtain optimal reinsurance strategy and investment strategy and optimal market strategy as well as the closed form expression of efficient frontier are obtained; finally get reinsurance strategy and optimal investment strategy and optimal market strategy as well as the closed form expression of efficient frontier for the original stochastic differential game.